>>35780https://www.sciencedirect.com/science/article/abs/pii/0022519377900443A major unresolved issue when dealing with the origin of life is that prebiotic syntheses invariably generate very heterogeneous solutions of organic compounds. This makes it impossible to imagine how ordered linear polymers, amino acids and nucleotides could be assembled. Prebiotic chemistry could produce a wealth of biomolecules from nonliving precursors. But the wealth would become overwhelming in the prebiotic soup and one cannot fathom how organized chemical processes could emerge from such a mess. At the heart of this problem is a dreary and vicious circle: what would be the selective force behind the evolution of the extremely complex translation system before there were functional proteins? There could be no proteins without a sufficiently effective translation system. How a random collection of proteins would assemble themselves into some kind of proto-cell capable of primitive replication is not even remotely answered. Modern cells require hundreds of proteins carrying out specific tasks when assembling a new protein molecule and if only a small portion of them were crudely made it is impossible to manufacture a new cell. The cells translational system is highly dependent on accurately made proteins and a faulty translational system is by default a biochemical paradox in evolutionary terms. A primitive cell is faced with an impossible task: in order to develop a more accurate translational system is has to translate more accurately. Each imperfect cycle introduces further errors and the cyclical nature of self-replication in the cell means that imperfections lead to autodestruction. A complex system like a cell cannot be gradually achieved because of its many complex and perfectly coadapted proteins.
https://newsroom.ucla.edu/releases/scientists-discover-organism-that-hasnt-evolved-in-more-than-2-billion-years>Scientists discover organism that hasn’t evolved in more than 2 billion yearshttps://www.nature.com/articles/d41586-022-01620-3>The long-term evolution experiment (LTEE) has become a cornerstone in evolutionary biology that researchers continue to mine for insights. During their 75,000 generations of growth, the bacteria have made huge gains in their fitness — how fast they grow relative to other bacteria — and evolved some surprising traits.https://journals.asm.org/doi/10.1128/JB.00831-15>The LTEE isolation of Cit+ mutants has become a textbook example of the power of long-term evolution to generate new species. But, based on our results, E. coli arrives at the same solution to access citrate in days versus years, as originally shown by Hall. In either case, genes involved in the process maintain their same function but show expanded expression by deregulation. Because of this, we argue that this is not speciation any more than is the case with any other regulatory mutant of E. coli.Even the "best" example of "evolution" has been debunked. E. coli have innate ability to change which does not involve any novel traits that appear out of nowhere.
Evolution is a cool story, though.
Flash Archive!
